They target gamma-aminobutyric acid chloride channels (GABACl) that aren't present in mammals. There is a relatively narrow therapeutic index in animals, but ge

They target gamma-aminobutyric acid chloride channels (GABACl) that aren't present in mammals. There is a relatively narrow therapeutic index in animals, but generally felt to be safe at approved doses. They're given to millions of animals, so we'd probably know if there was a problem.