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RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)
- yipbub 3y ago[flagged]
- LegitShady 3y agoMaybe you can ask chatgpt if people want to read about someone else asking it questions or not. Nobody cares what questions you typed into some llm front end. We can all do it to. If we wanted to we would. Instead we get no/low effort posts like yours.
- whalesalad 3y agothe beauty of having root access, as demonstrated by nature
- tomrod 3y agoWhat a wonderful way to see it. Medicine and biohacking are simply tools to improve evolutionary fitness.
- Idiot_in_Vain 3y agoThose are week tools. If you want to greatly improve your evolutionary fitness have as many kids as possible (preferably with multiple partners). E.g. sign up as a sperm donor.
- rob74 3y agoThis is purely speculation, but I wonder if this "root access" doesn't also come with downsides, e.g. more gene defects, which would help explain the short lifespan of most cephalopods.
- King-Aaron 3y ago* Deletes System32 * * dies *
- masklinn 3y agoIIRC it greatly limits the long-term flexibility, because most DNA changes will either break RNA edition or cascade into undesirable post-edition features. It's like taking a program at v0.1 and then developing the entire thing via binary patches, at one point you've got so much binary patching going on any edition and recompilation of the source makes them not work.
- natnat 3y agoPAPERCLIP
- ragebol 3y agoYeah, what's up with that? Do I have to pay them a beer now or something now that I found the marker word hidden in their paper they thought no one would read?
- alchemist1e9 3y agoIs there a connection to this and the supposed extraterrestrial retrovirus link to Cephalopods I’ve seen discussed within a Panspermia discussion? https://mindmatters.ai/2022/01/science-paper-could-octopuses-be-aliens-from-outer-space/ https://mindmatters.ai/2022/01/science-paper-could-octopuses...
- throwaway72762 3y agoWe have so much to learn from them. They diverged from us so long ago.
- jerojero 3y agoThey're cool but they're never taking over the planet. Suckers. On a more serious note, it's very interesting to see the different mechanisms that nature develops for adaptability. It seems like there's a trade off here between heredability and adaptability, with cephalopods favouring the second one. Meaning on a long scale their evolution might be slower but it allows them to overcome challenges on the short term more effectively. If I understood correctly, as I haven't read the whole thing yet.
- bad_alloc 3y ago> Suckers. Yes, they have those.
- dools 3y agoOn the one hand, we have digital watches. On the other hand, we may be about to bring about our own extinction and I'm willing to bet squid will be around no matter how much surface warming and sea level rise there is. Squid could well be the pinboard to our delicious ...
- tomohelix 3y ago> RNA editing, a post-transcriptional process, allows the diversification of proteomes beyond the genomic blueprint; however it is infrequently used among animals for this purpose. If I had written this and showed it to my PhD advisor, I would have gotten an earful about how "what do you mean by... be specific... what about...", etc. My PI was a nitpicker. Poor fools whose papers had to be edited by him... That said, RNA splicing is perhaps the single most important RNA editing process in the entire eukaryotic world. And it is so widespread and universally conserved that you can put a human gene in a mouse and it would be spliced the same way. So I don't think RNA editing is something so rare.
- jacquesm 3y agoThey split off so long ago that the most recent common ancestor of Cephalopods and mammals is a worm that lived ~500 million years ago: https://www.researchgate.net/figure/Phylogenetic-tree-depicting-the-evolutionary-relationship-between-cephalopods-and-the_fig1_344151907 https://www.researchgate.net/figure/Phylogenetic-tree-depict... That gives plenty of time for some mechanism to evolve in one of the two branches and not in the other. RNA editing may not be rare in that part of the evolutionary tree but I do wonder if it was already present in that common ancestor.
- dmix 3y agoI love those evolutionary trees. I recently read “The Rise and Reign of Mammals” [1] and it’s so interesting to find out that all mammals, and therefore humans, evolved from what was mostly a glorified ground squirrel (my words, not his). https://www.ucdavis.edu/curiosity/news/revealing-genome-common-ancestor-all-mammals https://www.ucdavis.edu/curiosity/news/revealing-genome-comm... [1] https://www.panmacmillan.com/authors/steve-brusatte/the-rise-and-reign-of-the-mammals/9781529034233 https://www.panmacmillan.com/authors/steve-brusatte/the-rise...
- adolph 3y agoSo long ago organs like eyes are an example of convergent evolution. https://evolution-outreach.biomedcentral.com/articles/10.1007/s12052-008-0084-1 https://evolution-outreach.biomedcentral.com/articles/10.100...
- Simon_O_Rourke 3y agoI for one welcome our new Cephalopod overlords, and remind them I could be useful in rounding up others to work in their underground sugar caves.
- gtsnexp 3y agoHere's a recent study employing modern imaging methods to observe and chart the activities in the brains of octopuses. It's quite surprising to find a high level of similarity with more advanced visual species. Functional organization of visual responses in the octopus optic lobe https://www.sciencedirect.com/science/article/pii/S0960982223007455?dgcid=raven_sd_aip_email https://www.sciencedirect.com/science/article/pii/S096098222...