Yes this is what I do, and I wouldn't have dedupe for all datasets, for instance in this case he wanted dedupe on his games, so I would just enable it for that

Yes this is what I do, and I wouldn't have dedupe for all datasets, for instance in this case he wanted dedupe on his games, so I would just enable it for that dataset. But I do run disk-wide compression with no problems and have done so on all my datasets for many years now, and it's been a tremendous space saver. Especially on machines where I have a lot of VMs/containers, it's not unusual for me to have a compression ratio of 2 on these with good old lz4, it will be interesting to see what damage zstd will do once I start experimenting with that.