5 ms·
From the article: "yet it doesn’t seem to be important for normal development" Gene space is huge. My cancer is cured, but now I'm dying of mange. So that's w
by steve76 5y ago
From the article:
"yet it doesn’t seem to be important for normal development"
Gene space is huge. My cancer is cured, but now I'm dying of mange. So that's why that mouse kept licking itself. Big ask for someone else. They have trouble getting blood thinners, statins and beta blockers right. And there's no genetics there. It's stuff people ate out in the woods for hundreds of thousands of years.
> There are so many people close to dying in cancer finding volunteers for a Phase 1 test should be easy
I take the opposite approach. These people have few days left. It's a time to make things nice. It can get much worse quick. Cancer, which can be managed, is nowhere near as bad as it can get.
Disease tends to hit all at once. It's really just dying. Cancer, strokes, heart attacks and infections all tend to gang up at once. The trial will kill these people no doubt. If you have a ticket out of the hospital, take it! Don't squander it trying to wash mud.
Also the patient pays a lot for clinical trials. Hundreds of thousands of dollars.
- verve_rat 5y agoWait what? Trails aren't free to participants? That alone is going to majorly bias the results. Here take this medicine, we are fairly confident it won't kill you. Here is your $100k bill. Oh? Can't afford that? No trial for you!
- zaroth 5y agoTrials are absolutely free for the participants. Insurance won’t pay for non-FDA approved treatments and it’s illegal to charge for them anyway. Ancillary routine FDA approved testing that accompanies the trials may be billed to insurance in some cases? I don’t know about that. But a trial for a novel cancer treatment will be free, if not even include an honorarium of some kind to defray costs to the patient for participating.
- tharkun__ 5y agoYou seem to be getting downvoted. Not sure why. I've had someone in the family who got cancer. It was basically how you said it would be. They lived their life to the fullest, not thinking about the untreatable cancer. Do whatever is fun and makes you happy. At some point it got bad. No more living your life. There were bad moment. There were better moments. There were worse moments. I only saw it from afar until the very end. The last bit must have been hell for the closest family. It really is just dying. Slowly. Painfully. And all society and doctors try to do is to prolong the suffering. I'm being unfair to some people. I do know the palliative care team did their best. All volunteer doctors. Power to them.
- kens 5y agoGenerally patients don't pay extra for clinical trials, although it's complicated. Their insurance usually pays for patient care costs, routine costs you'd have regardless of the trial. The trial usually pays for research costs, tests and stuff specifically due to the research. https://www.mskcc.org/cancer-care/clinical-trials/frequently-asked-questions#do-i-have-to-pay-to-be-in-a-clinical-trial- https://www.mskcc.org/cancer-care/clinical-trials/frequently...
- oleander73 5y agoAgreed (except the part about the patient paying for clinical trials). After I got diagnosed with metastatic prostate cancer last year I was asked to participate in a immunotherapy trial. I declined as a wasn't about to spend the next two years (that could very well be my last) going to the hospital every three weeks to be poked and prodded.