4 ms·
Sorry it didn’t land with you. We’re constantly torn between writing for the one person (a healthcare provider) vs a larger population. An example question is
by aadvani 6y ago
Sorry it didn’t land with you. We’re constantly torn between writing for the one person (a healthcare provider) vs a larger population.
An example question is a fantastic idea and will land with both audiences :-)
We’ll get our top three most recent on the homepage ASAP but in the meantime:
If you have a typical late stage COVID patient, a static patient resource like you described is perfectly fine to look at efficacy of the standard dexamethasone 6mg treatment.
But if you have an atypical patient and considering a 20mg dose, you’re out of luck. Most patients are atypical and we see an unmet need with a long tail of atypical questions.
- Herodotus38 6y agoTypical dose of dexamethasone is 6 mg not 4 mg. And only in severe cases needing oxygen, not early.
- aadvani 6y agoThanks for the correction I actually typed 6 every 24 but found it confusing and resulted in error, fixed now
- aadvani 6y agoAlso, we actually did this one, if you’re curious: https://www.inpharmd.com/is-there-any-data-to-support-higher-doses-of-dexamethasone-than-6-mg-daily-for-covid-19 https://www.inpharmd.com/is-there-any-data-to-support-higher...
- Herodotus38 6y agoThanks for the link. Anecdotally in our hospital only one patient to my knowledge has survived after a higher dose of dexamethasone (this was only used after the patient was worsening despite the standard 10 days of 6 mg dexamethasone). Whether this helped them or they were going to improve despite can't be known. I would also be careful about how you use the term atypical, in fact most patients with COVID are typical and improve with the standard treatment. :)
- aadvani 6y agoGreat info, and a shame there’s not better real world evidence for cases like this. And I hear you, just making the point that most shouldn't be considered “typical”; we should question everything.