12 ms·

Ebola Is Now a Disease We Can Treat

346 points by muriithi 7y ago

justboxing 7y ago
Paywall.
- windsurfer 7y ago
  Just clear your site cookies and refresh.
  - rb808 7y ago
    which one lol. My browser says its using 243, just incredible.
    - johnweldon 7y ago
      Even opening in a clean incognito window hits the paywall
    - windsurfer 7y ago
      On Firefox I just had to clear the *.wsj.com cookies and then refresh.
      - gpm 7y ago
        Also on firefox, right click "open in new private window" worked... but I don't think it always does. Maybe something to do with my ip address?
        PhasmaFelis 7y ago
        Recently some sites are using HTML5 client-side storage for their paywalls, not just cookies. Forget Me for Chrome seems to get them all, though. https://chrome.google.com/webstore/detail/forget-me-clean-history-c/gekpdemielcmiiiackmeoppdgaggjgda https://chrome.google.com/webstore/detail/forget-me-clean-hi...
        latchkey 7y ago
        Also. https://chrome.google.com/webstore/detail/clear-session/maejjihldgmkjlfmgpgoebepjchengka?hl=en https://chrome.google.com/webstore/detail/clear-session/maej...
  - aerovistae 7y ago
    that doesn't work on wsj.
    - windsurfer 7y ago
      Worked for me on Firefox. I'm not sure why.
- dang 7y ago
  Please don't post unsubstantive comments here. The paywall issue has been discussed extensively. If there's a workaround, it's ok. Users usually post workarounds in the threads. This is in the FAQ at https://news.ycombinator.com/newsfaq.html https://news.ycombinator.com/newsfaq.html and there's more explanation here: https://news.ycombinator.com/item?id=10178989 https://news.ycombinator.com/item?id=10178989 https://hn.algolia.com/?sort=byDate&dateRange=all&type=comment&storyText=false&prefix&page=0&query=by:dang%20paywall https://hn.algolia.com/?sort=byDate&dateRange=all&type=comme...
deleted 7y ago
[deleted]
adventured 7y ago
https://outline.com/zXFSvv https://outline.com/zXFSvv
- thedaemon 7y ago
  Outline works, this link is valid.
- qwerty456127 7y ago
  Thanks! By the way, if somebody happens to know a Python (or whatever) library/example which can do a job similar to what Outline does extracting and tidying pure content from a web page - let me know please. I don't plan any mass-scraping, just want to save some stuff for myself for offline reading.
  - franey 7y ago
    I've used this wrapper[0] for Firefox's reader mode[1], and it worked well: [0] https://www.npmjs.com/package/readability-wrapper https://www.npmjs.com/package/readability-wrapper [1] https://github.com/mozilla/readability https://github.com/mozilla/readability
  - nullify88 7y ago
    I've recently changed a habit of mine where I amass a huge list of bookmarks or files that I'll "read later". I've owned a Kindle for a while now and recently had the idea that I can use the sendtokindle extension to send and store my articles for offline reading. I find it's easier to read the content and my Kindle is usually with me for times I want to read unlike my laptop with all the weight and distractions that come with it. https://www.amazon.com/gp/sendtokindle https://www.amazon.com/gp/sendtokindle
deleted 7y ago
[deleted]
baxtr 7y ago
Clever strategy Dr. Muyembe set out on his path to an Ebola treatment during the 1995 outbreak. He transferred blood from five survivors to eight patients, hoping that the antibodies that kept some people alive would keep others from dying. Seven of the patients who received the blood transfusion recovered.
- markdown 7y ago
  It's the first thing I'd try... because I've seen it done in movies.
- akiselev 7y ago
  I wonder what an Ethics Review Board would have to say about this...
  - baldfat 7y ago
    Well lets see? It had a 90% death rate as a disease I would gladly give, receive or beg for it for myself or my child.
    - Iv 7y ago
      Note that the survivability of Ebola is much higher if you are in an hospital. Basically, if you have access to IV hydration.
  - deleted 7y ago
    [deleted]
  - zamadatix 7y ago
    About what particularly? Blood transfusions in general are neither new nor rare.
  - __s 7y ago
    Note it's survivors, not still sick patients, having their blood taken
  - Fomite 7y ago
dielll 7y ago
paywall
billfruit 7y ago
There was some news regarding the use of malariotherapy for Ebola, indicating some promise, from couple of years ago. Did not hear any more about it since then.
COGlory 7y ago
Worth pointing out that there are two Ebola vaccines on the market. One is a recombinant vesticular stomavirus, VSV-EBOV, that was engineered to express an Ebola glycoprotein. It was found to be reliably efficient up to 5 days before infection in macaques. It requires only one dose to be effective, because the VSV will replicate in the host to some degree (asymptomatically) and produce a strong immune response. There is also another 2-dose vaccine that is actually being distributed. I don't know much about it, but requiring a second dose likely means it's a protein fragment or attenuated Ebola virus, likely making it more heat stable and actually easier to distribute. Compliance is an issue, but it has proven effective in ring vaccination usage (vaccination of those around people who have contracted the disease). There's also been some initiative to grow human Ebola antibodies in crops and distribute those as well. As usual, the primary challenge to stopping Ebola spread is the political and social climate in the war torn DRC.
est 7y ago
What happened to the Chinese scientist who developed the Ebola cure ZMapp? https://www.cbc.ca/news/canada/manitoba/ebola-henipah-china-1.5232674 https://www.cbc.ca/news/canada/manitoba/ebola-henipah-china-...
- capableweb 7y ago
  This seems to be the latest news on it: > In August 2019, the Democratic Republic of the Congo’s national health authorities, the World Health Organization, and the National Institutes of Health announced that they would stop using ZMapp, along with all other Ebola treatments except REGN-EB3 and mAb114, in their ongoing clinical trials, citing the higher mortality rates of patients not treated with REGN-EB3 and mAb114 From https://en.wikipedia.org/wiki/ZMapp#Use_during_the_2014%E2%80%9316_Ebola_outbreak_in_West_Africa https://en.wikipedia.org/wiki/ZMapp#Use_during_the_2014%E2%8... So seems it's just used in some cases today.

346 points by muriithi 7y ago

justboxing 7y ago

Paywall.

windsurfer 7y ago
Just clear your site cookies and refresh.
- rb808 7y ago
  which one lol. My browser says its using 243, just incredible.
  - johnweldon 7y ago
    Even opening in a clean incognito window hits the paywall
  - windsurfer 7y ago
    On Firefox I just had to clear the *.wsj.com cookies and then refresh.
    - gpm 7y ago
      Also on firefox, right click "open in new private window" worked... but I don't think it always does. Maybe something to do with my ip address?
      - PhasmaFelis 7y ago
        Recently some sites are using HTML5 client-side storage for their paywalls, not just cookies. Forget Me for Chrome seems to get them all, though. https://chrome.google.com/webstore/detail/forget-me-clean-history-c/gekpdemielcmiiiackmeoppdgaggjgda https://chrome.google.com/webstore/detail/forget-me-clean-hi...
        latchkey 7y ago
        Also. https://chrome.google.com/webstore/detail/clear-session/maejjihldgmkjlfmgpgoebepjchengka?hl=en https://chrome.google.com/webstore/detail/clear-session/maej...
- aerovistae 7y ago
  that doesn't work on wsj.
  - windsurfer 7y ago
    Worked for me on Firefox. I'm not sure why.
dang 7y ago
Please don't post unsubstantive comments here. The paywall issue has been discussed extensively. If there's a workaround, it's ok. Users usually post workarounds in the threads. This is in the FAQ at https://news.ycombinator.com/newsfaq.html https://news.ycombinator.com/newsfaq.html and there's more explanation here: https://news.ycombinator.com/item?id=10178989 https://news.ycombinator.com/item?id=10178989 https://hn.algolia.com/?sort=byDate&dateRange=all&type=comment&storyText=false&prefix&page=0&query=by:dang%20paywall https://hn.algolia.com/?sort=byDate&dateRange=all&type=comme...

deleted 7y ago

[deleted]

adventured 7y ago

https://outline.com/zXFSvv https://outline.com/zXFSvv

thedaemon 7y ago
Outline works, this link is valid.
qwerty456127 7y ago
Thanks! By the way, if somebody happens to know a Python (or whatever) library/example which can do a job similar to what Outline does extracting and tidying pure content from a web page - let me know please. I don't plan any mass-scraping, just want to save some stuff for myself for offline reading.
- franey 7y ago
  I've used this wrapper[0] for Firefox's reader mode[1], and it worked well: [0] https://www.npmjs.com/package/readability-wrapper https://www.npmjs.com/package/readability-wrapper [1] https://github.com/mozilla/readability https://github.com/mozilla/readability
- nullify88 7y ago
  I've recently changed a habit of mine where I amass a huge list of bookmarks or files that I'll "read later". I've owned a Kindle for a while now and recently had the idea that I can use the sendtokindle extension to send and store my articles for offline reading. I find it's easier to read the content and my Kindle is usually with me for times I want to read unlike my laptop with all the weight and distractions that come with it. https://www.amazon.com/gp/sendtokindle https://www.amazon.com/gp/sendtokindle

deleted 7y ago

[deleted]

baxtr 7y ago

Clever strategy Dr. Muyembe set out on his path to an Ebola treatment during the 1995 outbreak. He transferred blood from five survivors to eight patients, hoping that the antibodies that kept some people alive would keep others from dying. Seven of the patients who received the blood transfusion recovered.

markdown 7y ago
It's the first thing I'd try... because I've seen it done in movies.
akiselev 7y ago
I wonder what an Ethics Review Board would have to say about this...
- baldfat 7y ago
  Well lets see? It had a 90% death rate as a disease I would gladly give, receive or beg for it for myself or my child.
  - Iv 7y ago
    Note that the survivability of Ebola is much higher if you are in an hospital. Basically, if you have access to IV hydration.
- deleted 7y ago
  [deleted]
- zamadatix 7y ago
  About what particularly? Blood transfusions in general are neither new nor rare.
- __s 7y ago
  Note it's survivors, not still sick patients, having their blood taken
- Fomite 7y ago

dielll 7y ago

paywall

billfruit 7y ago

There was some news regarding the use of malariotherapy for Ebola, indicating some promise, from couple of years ago. Did not hear any more about it since then.

COGlory 7y ago

Worth pointing out that there are two Ebola vaccines on the market. One is a recombinant vesticular stomavirus, VSV-EBOV, that was engineered to express an Ebola glycoprotein. It was found to be reliably efficient up to 5 days before infection in macaques. It requires only one dose to be effective, because the VSV will replicate in the host to some degree (asymptomatically) and produce a strong immune response. There is also another 2-dose vaccine that is actually being distributed. I don't know much about it, but requiring a second dose likely means it's a protein fragment or attenuated Ebola virus, likely making it more heat stable and actually easier to distribute. Compliance is an issue, but it has proven effective in ring vaccination usage (vaccination of those around people who have contracted the disease). There's also been some initiative to grow human Ebola antibodies in crops and distribute those as well. As usual, the primary challenge to stopping Ebola spread is the political and social climate in the war torn DRC.

est 7y ago

What happened to the Chinese scientist who developed the Ebola cure ZMapp? https://www.cbc.ca/news/canada/manitoba/ebola-henipah-china-1.5232674 https://www.cbc.ca/news/canada/manitoba/ebola-henipah-china-...

capableweb 7y ago
This seems to be the latest news on it: > In August 2019, the Democratic Republic of the Congo’s national health authorities, the World Health Organization, and the National Institutes of Health announced that they would stop using ZMapp, along with all other Ebola treatments except REGN-EB3 and mAb114, in their ongoing clinical trials, citing the higher mortality rates of patients not treated with REGN-EB3 and mAb114 From https://en.wikipedia.org/wiki/ZMapp#Use_during_the_2014%E2%80%9316_Ebola_outbreak_in_West_Africa https://en.wikipedia.org/wiki/ZMapp#Use_during_the_2014%E2%8... So seems it's just used in some cases today.