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byteCoder
searching Neon…
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11 ms
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31.
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by
byteCoder
8y ago
Yes, for the two days of high dose IL-2 every 8 hours, it was pretty bad. My experience was limited to nausea, fever, sweating, and bed-shaking rigors. I've heard that some patients experience hallucinations. Note: IL-2 was administere
32.
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byteCoder
8y ago
I’m now 5.5 years post-treatment with immunotherapy for Stage IV melanoma and have had no evidence of disease for over four years. When immunotherapy works, it can be impressive. For me, my treatment (adoptive cell therapy using tumor infil
33.
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by
byteCoder
8y ago
This was demonstrated on "Mythbusters" in 2013: "Hot-air hand dryers are less sanitary than paper towels in public restrooms. CONFIRMED In a preliminary test, Adam and Jamie found that washing their hands properly with soap d
34.
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by
byteCoder
8y ago
For weight loss, diet is more important than exercise, by far. There are several aphorisms about this: 1. "Abs are made in the kitchen." 2. "You can't outrun a bad diet." Personally, I've found that carb restri
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GoPro has discontinued its developer program
(developer.gopro.com)
115 points
by
byteCoder
9y ago
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92 comments
36.
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by
byteCoder
9y ago
I suspect that Richard's first computer was an Apple ][+, not an Apple //e (as claimed by the article), as Ultima existed (published 1981) well before the Apple //e was released (1983).
37.
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byteCoder
9y ago
Here's a good, quick review of the case-law precedents regarding free expression in quasi-public places in the United States: http://law.justia.com/constitution/us/amendment-01/54-quasi-...
38.
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by
byteCoder
9y ago
Nope. As far as I know, I've retained my immunities. However, I do know that my seasonal allergies have changed slightly since treatment–they've actually moderated. I don't know if that's due to the treatment or just an
39.
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by
byteCoder
9y ago
My melanoma was initially an ugly black mole that grew on the side of my face, which I had removed by my dermatologist and sent to pathology for analysis, where it was determined to be a melanoma of intermediate depth. Because of its depth
40.
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by
byteCoder
9y ago
The research doctors at NIH have been refining treatments with IL-2 for almost two decades for thousands of patients. They've gotten enough experience to recognize and mitigate the issues that may develop. In my specific case, they wee
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by
byteCoder
9y ago
My biggest side effect has been vitiligo, the loss of color in my skin. The treatment caused my immune system to attack my melanocytes in addition to my melanoma cells. This is actually a great prognostic indicator. If that's the worst
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byteCoder
9y ago
I don't know all the technical measurements and details, but, yes, the researchers did feed them parts of my tumor.
43.
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byteCoder
9y ago
Absolutely agreed.
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byteCoder
9y ago
I hope that I'm wrong. Many more patients can possibly be saved with more widespread use of this treatment. Of course, the FDA needs to modernize their own approval processes to deal with such personalized treatments. It's my unde
45.
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by
byteCoder
9y ago
Since this was conducted under a research trial by the US government, the treatment did not cost me (or my health insurance) a penny. I am told that the treatment and follow-ups cost the research program budget at least a million dollars pe
46.
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by
byteCoder
9y ago
You've listed the main side effects of the treatment: pain, fever, and delirium. About 20-30 minutes after receiving a dose of IL-2 by infusion, my body would undergo violent bed-shaking rigors for 10-20 minutes. I had the worst chills
47.
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by
byteCoder
9y ago
Also, besides the overall success of my treatment, other than regular followup scans, I don't require any further medications of any sort. It's a one-and-done treatment. I'm certain that Big Pharma doesn't like these tre
48.
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by
byteCoder
9y ago
Five years ago, I had my own immune system rebooted to (so far) eliminate my Stage IV melanoma cancer in a trial at the National Institutes of Health. At that time, without further treatment, I probably had six to twelve months to live. In
49.
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by
byteCoder
10y ago
As a young widower myself, I can relate to many of the emotions and grief expressed in the article. It's actually no surprise that I ended up meeting, connecting with, and eventually marrying someone who was widowed in her 30s. From th
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byteCoder
10y ago
Abstract Physical activity is associated with reduced risk of several cancers, including aggressive prostate cancer. The mechanisms mediating the effects are not yet understood; among the candidates are modifications of endogenous hormone l
51.
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byteCoder
11y ago
I'm currently almost 3.5 years post-treatment in one of Dr. Steven Rosenberg's adoptive cell therapy trials for Stage IV melanoma (which were mentioned in the article). I'm one of the lucky patients (20+%) who have experience
52.
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byteCoder
11y ago
Looking at their score example at the bottom of the page, the right-hand score is defined as a separate entity from the left-hand score. As a result, to the OMN notation reader, it's hard to see the inherent synchrony between the two h
53.
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byteCoder
12y ago
Immunotherapy absolutely works for melanoma–I'm living proof. As a Stage IV melanoma survivor, immunotherapy via a tumor infiltrating lymphocytes (TIL) trial at NIH has extended (if not saved) my life. I'm over two years out from
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byteCoder
12y ago
Following the tradition of sports, I propose that commit id e83c5163316f89bfbde7d9ab23ca2e25604af290 be officially retired.
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byteCoder
12y ago
Of course, we never hear about all the times the system has given false positives.
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byteCoder
12y ago
This critique appears to be projecting its author's desire for a solution to the EHR compatibility problem on to Apple. I haven't seen anything from Apple indicating that HealthKit is the answer to this problem. HealthKit provides
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byteCoder
12y ago
Reading his blog, it appears he went though a similar immunotherapy trial at NIH that I underwent almost two years ago (mine for melanoma). I'm saddened to hear that it was not successful for him. Immunotherapy treatments continue to i
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iPads and the Embarrassment Factor
(chronicle.com)
2 points
by
byteCoder
15y ago
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0 comments
59.
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by
byteCoder
15y ago
Certainly, it appears that the insert and delete key icons are based on classic proofreader's marks. The caret above the "a" means insert. The a with the looped line through it means delete.
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byteCoder
16y ago
Although I do prefer the idea that all peer reviewers are transparent, anonymous peer review isn't the problem per se—it's really the lack of oversight of the anonymous reviewers by the journal editorial staff that's the real problem. The e
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