6 ms·

I also have IBS and was diagnosed years ago, but I never heard of different classifications that you mentioned, IBS-C or IBS-D. Mostly, I classify the severity

I also have IBS and was diagnosed years ago, but I never heard of different classifications that you mentioned, IBS-C or IBS-D. Mostly, I classify the severity as "day-to-day", workdays usually being the worst. I haven't tried consuming live cultures other than yogurt, and even then I have mixed results. Have you gotten far in your research on the types of bacteria, and do you have any resources you could share? Edit: just read about differences between IBS-C and D and it definitely sounds like there has been some headway in the last 15 years since I was diagnosed (back then it was mostly a prognosis of "here's a colonoscopy, sorry not much else we can do"). I should definitely get re-evaluated. Thanks for mentioning this.

bignaj 12y ago
C is constipation. D is diarrhea. I have Crohn's and didn't know these either, but Google was my friend. I personally don't distinguish. Diarrhea largely affects individuals who have Crohn's in the colon (not me) due to the colon's role in body water absorption from fecal waste. My inflammation occurs in the ileum so I rarely, if ever, have diarrhea but I do have severe, piercing abdominal pain from scar tissue and constriction. My personal opinion from a biology background is we largely don't know jack about Crohn's/IBS and the classifications are grasping at straws. If you do want to know some of the scientific stuff the genetics side is a great place to start. NOD2 is specifically involved in Crohn's: http://en.wikipedia.org/wiki/NOD2 http://en.wikipedia.org/wiki/NOD2 and you can learn a lot of interesting things about our innate immune system.
jmhain 12y ago
From the little research I've done, it looks like the bifidobacterium genus, in particular certain strains of bifidobacterium longum [0,1] and infantis [2], have favorable effects on IBS and anxiety. Interestingly, in [1] they noted that it was able to normalize low BDNF levels, which is one hypothesis as to how SSRIs treat anxiety and depression. However, I picked out my probiotic specifically because it has those species (among many others), and you read what happened. [0] http://www.ncbi.nlm.nih.gov/pubmed/17172187 http://www.ncbi.nlm.nih.gov/pubmed/17172187 [1] http://www.apa.org/monitor/2012/09/gut-feeling.aspx http://www.apa.org/monitor/2012/09/gut-feeling.aspx [2] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886445/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886445/

bignaj 12y ago

C is constipation. D is diarrhea. I have Crohn's and didn't know these either, but Google was my friend. I personally don't distinguish. Diarrhea largely affects individuals who have Crohn's in the colon (not me) due to the colon's role in body water absorption from fecal waste. My inflammation occurs in the ileum so I rarely, if ever, have diarrhea but I do have severe, piercing abdominal pain from scar tissue and constriction. My personal opinion from a biology background is we largely don't know jack about Crohn's/IBS and the classifications are grasping at straws. If you do want to know some of the scientific stuff the genetics side is a great place to start. NOD2 is specifically involved in Crohn's: http://en.wikipedia.org/wiki/NOD2 http://en.wikipedia.org/wiki/NOD2 and you can learn a lot of interesting things about our innate immune system.

jmhain 12y ago

From the little research I've done, it looks like the bifidobacterium genus, in particular certain strains of bifidobacterium longum [0,1] and infantis [2], have favorable effects on IBS and anxiety. Interestingly, in [1] they noted that it was able to normalize low BDNF levels, which is one hypothesis as to how SSRIs treat anxiety and depression. However, I picked out my probiotic specifically because it has those species (among many others), and you read what happened. [0] http://www.ncbi.nlm.nih.gov/pubmed/17172187 http://www.ncbi.nlm.nih.gov/pubmed/17172187 [1] http://www.apa.org/monitor/2012/09/gut-feeling.aspx http://www.apa.org/monitor/2012/09/gut-feeling.aspx [2] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886445/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886445/