I'd use it full-screen with pyGame and experiment with implementing the view part of MVC and alternative user interface (that requires no keyboard nor mouse) th

I'd use it full-screen with pyGame and experiment with implementing the view part of MVC and alternative user interface (that requires no keyboard nor mouse) think gestures, taps, etc. Direct manipulation has a huge promise when applied on a larger scale. Look at iPhone / iPod Touch and the various Surface systems for inspiration.