7 ms·

The question is: does it increase muscle nuclei or just water volume?

• upheaval7276 5d ago
  good question, and DXA won't tell you the answer there (they used DXA in the study) So not an especially convincing study in that case, since creatine leads to increased water retention.
• IncreasePosts 5d ago
  (A meta analysis) https://pmc.ncbi.nlm.nih.gov/articles/PMC5679696/?utm_source=gemini#sec3 https://pmc.ncbi.nlm.nih.gov/articles/PMC5679696/?utm_source... > For example, over 8 weeks of resistance training in young men, creatine supplementation resulted in a faster increase in satellite cell number, myonuclei per muscle fiber, and muscle fiber size.
  • upheaval7276 5d ago
    that's an entirely different study with different goals
    • IncreasePosts 5d ago
      The question was asked whether creatine increases muscle nuclei or just water volume, and I provided a study (well, a meta-study which is referring to a specific study) which showed that creatine supplementation increased the muscle nuclei compared to no supplementation. The specific study referred to is titled "Creatine supplementation augments the increase in satellite cell and myonuclei number in human skeletal muscle induced by strength training"
      • upheaval7276 5d ago
        the interesting claim about the study in the OP is that creatine increases muscle mass in non-trained/sedentary individuals. i haven't seen that claim previously (backed by a study) and took the question from user "15155" to be about that specifically. the claim that it increases muscle mass when combined with resistance training seems to be long-settled though
  • 15155 5d ago
    > resistance training Yes, but what about sedentary individuals?