7 ms·
Maybe. Maybe not. Look at AI drug design - it's not really speeding up the important part - drug trials. There isn't really a coherent plan to use AI for the mo
by danielmarkbruce 8d ago
Maybe. Maybe not. Look at AI drug design - it's not really speeding up the important part - drug trials. There isn't really a coherent plan to use AI for the most complex part of drug discovery at all.
- brettdev 6d agoScience is more than just drugs
- dekhn 7d agoI work in pharma and I've advocated for directly training models that predict drug trial outcomes. I don't think we have the necessary support (data + algorithms) to produce accurate models in this space. I suspect that predicting drug trial outcomes is roughly isomorphic to understanding human biology at a fundamental level (and accepting that our existing models of how drugs work are extremely limited).
- danielmarkbruce 7d agoAgree, it is effectively understanding human biology - which we suck at, have little data on, have few good models for. So, it doesn't appear there is any way to avoid the clinical trial process. And it won't speed up, and it won't get cheaper. Am I wrong?