Assuming you had a 1:1 scale, what would be the difference between you taking a camera of an environment and measuring everything the same way vs. it being gene

Assuming you had a 1:1 scale, what would be the difference between you taking a camera of an environment and measuring everything the same way vs. it being generated artificially in a 3d space? Wouldn't the inputs be more or less the same wrt training a model with the synthetic data vs live video and the data captured there?