I generally set up the rules of engagement for a project in the AGENTS.md file and if it starts to get large break out to more specific files referenced from AG

I generally set up the rules of engagement for a project in the AGENTS.md file and if it starts to get large break out to more specific files referenced from AGENTS.md to keep the constant per-request token overhead lower. For Python, I have the agent use `uv` (even for direct script invocations) so that the agent doesn't need to burn tokens concerning itself with the details that `uv` is managing behind the scenes.