24 ms·
Lookup "occupancy chart antidepressant", study the chart. There is an exponential drop-off at lower doses. Hence to taper off without feeling it, one needs to c
by ernsheong 20d ago
Lookup "occupancy chart antidepressant", study the chart. There is an exponential drop-off at lower doses. Hence to taper off without feeling it, one needs to cut smaller and smaller doses, (or liquify) which may be impractical.
- mrec 20d agoInteresting; I wasn't aware that 20mg was considered the minimum effective dose for fluoxetine. I tried tapering from 20mg to 15mg (alternating 10/20) after ~4 years and was absolutely fine; I then tried the next step down to 10mg and crashed hard. Probably going to stay on it for life now, which is fine; I never really experienced any negative side effects.
- ernsheong 20d agoWith this chart we now know why stepping down from 15mg to 10mg is a HUGE step.
- mrec 20d agoCould you link to the specific chart you're looking at? I think our searches are finding different things.
- ernsheong 19d agohttps://www.madinamerica.com/2021/09/antidepressant-effects-serotonin-plateau-minimum-recommended-dose/ https://www.madinamerica.com/2021/09/antidepressant-effects-... and its variants