You would get a lot of differences, but the errors would cancel each other out with enough depth of coverage. This technology's baseline accuracy is around 95%

You would get a lot of differences, but the errors would cancel each other out with enough depth of coverage. This technology's baseline accuracy is around 95% per base, so 10x reads of every segment in the sample would give >99% accuracy for each base after aligning the reads with each other. https://en.wikipedia.org/wiki/Coverage_(genetics) https://en.wikipedia.org/wiki/Coverage_(genetics)