this is essentially how bindcraft works for drug discovery: https://www.nature.com/articles/s41586-025-09429-6 https://www.nature.com/articles/s41586-025-09429-

this is essentially how bindcraft works for drug discovery: https://www.nature.com/articles/s41586-025-09429-6 https://www.nature.com/articles/s41586-025-09429-6 (minus the accumulation step) feedback from af2 folding confidence + structural scoring