5 ms·

Yup - in the UK, paracetamol is usually recommended for general pain relief before Ibuprofen. Additionally, Ibuprofen and NSAIDs have a lot of interactions whic

Yup - in the UK, paracetamol is usually recommended for general pain relief before Ibuprofen. Additionally, Ibuprofen and NSAIDs have a lot of interactions which can make them unsafe - SSRIs or blood thinners for example.

lloydatkinson 5mo ago
Where does Aspirin fit into this? I only use paracetemol and ibuprofen. The one time I tried asprin I got a stomach pain.
- mrcrm9494 5mo ago
  aspirin is an NSAID, taking it modifies the prostaglandine levels (through its COX inhibition) and this influences the mucosa of your stomach. ibuprofen can still have the same side effects, because its belonging to the same class of drugs.
mghackerlady 5mo ago
Ibuprofen interacts with SSRIs? Anecdotally I've never had any problems with my Escitalopram and the Wikipedia page doesn't mention any interactions
- magicalhippo 5mo ago
  The Norwegian pages I linked to states you should be careful with Ibuprofen and anti-depressants. I did a quick search and these[1][2] articles came up, suggesting increased risk of brain hemorrhaging and 10x increased gastrointestinal adverse effects due to the combination. [1]: https://www.cam.ac.uk/research/discussion/antidepressants-and-pain-killers-should-we-be-worried https://www.cam.ac.uk/research/discussion/antidepressants-an... [2]: https://pmc.ncbi.nlm.nih.gov/articles/PMC1884970/ https://pmc.ncbi.nlm.nih.gov/articles/PMC1884970/