6 ms·

four figures these days. fits in your hand. nanopore is a revolution. https://nanoporetech.com/products/sequence/minion https://nanoporetech.com/products/sequen

by cmrx64 5mo ago

four figures these days. fits in your hand. nanopore is a revolution. https://nanoporetech.com/products/sequence/minion https://nanoporetech.com/products/sequence/minion there’s youtubers that have videos about doing this in a home wetlab. very achievable. some amateur soil biologists using this to try and sample microdiversity as the planet… humanifies.

dubi_steinkek 5mo ago
Do you have links to these youtubers? Sounds interesting
- samplatt 5mo ago
  Not OP, but The Thought Emporium is a personal favourite. Their name belies the hands-on nature of their videos. https://www.youtube.com/watch?v=F0_q-fD_lyU https://www.youtube.com/watch?v=F0_q-fD_lyU
robertlagrant 5mo ago
Ex-Nanopore employee here. One interesting thing we heard about internally was that OceanX[0] has one of our GridION[1] devices (slightly larger, and built-in compute) that they were using to track whales in the ocean by sequencing DNA found in seawater. Really cool. [0] https://en.wikipedia.org/wiki/OceanX https://en.wikipedia.org/wiki/OceanX [1] https://nanoporetech.com/products/sequence/gridion https://nanoporetech.com/products/sequence/gridion
- netcraft 5mo ago
  huge if true had an episode about this recently https://www.youtube.com/watch?v=0HlLwG2xN_c https://www.youtube.com/watch?v=0HlLwG2xN_c
the__alchemist 5mo ago
I have a mol bio home lab, and decided against it because while the devices themselves are reasonably priced, the flow cells are an expensive disposable. I use Plasmidsaurus instead: Pay them $15/sample online, drop off the tubes in a styrophoam box labeled with a dinosaur in a nearby university building; get the results next morning. They use Oxford Nanopore, but are loading your sample along with many other samples to maximize flow cell use.
- butvacuum 5mo ago
  not suprised. the website seemed to indicate to me (a layman in this area) that it expired based on time, not use- so Seqiencing As A Service (ha!) makes financial sense for most people.

by cmrx64 5mo ago

dubi_steinkek 5mo ago

Do you have links to these youtubers? Sounds interesting

samplatt 5mo ago
Not OP, but The Thought Emporium is a personal favourite. Their name belies the hands-on nature of their videos. https://www.youtube.com/watch?v=F0_q-fD_lyU https://www.youtube.com/watch?v=F0_q-fD_lyU

robertlagrant 5mo ago

Ex-Nanopore employee here. One interesting thing we heard about internally was that OceanX[0] has one of our GridION[1] devices (slightly larger, and built-in compute) that they were using to track whales in the ocean by sequencing DNA found in seawater. Really cool. [0] https://en.wikipedia.org/wiki/OceanX https://en.wikipedia.org/wiki/OceanX [1] https://nanoporetech.com/products/sequence/gridion https://nanoporetech.com/products/sequence/gridion

netcraft 5mo ago
huge if true had an episode about this recently https://www.youtube.com/watch?v=0HlLwG2xN_c https://www.youtube.com/watch?v=0HlLwG2xN_c

the__alchemist 5mo ago

I have a mol bio home lab, and decided against it because while the devices themselves are reasonably priced, the flow cells are an expensive disposable. I use Plasmidsaurus instead: Pay them $15/sample online, drop off the tubes in a styrophoam box labeled with a dinosaur in a nearby university building; get the results next morning. They use Oxford Nanopore, but are loading your sample along with many other samples to maximize flow cell use.

butvacuum 5mo ago
not suprised. the website seemed to indicate to me (a layman in this area) that it expired based on time, not use- so Seqiencing As A Service (ha!) makes financial sense for most people.