8 ms·

Tbh, it's not clear that if we all stopped drinking the world would be better.

• gtowey 1y ago
  Yeah, and maybe it would be better still if we all tried heroin!
  • Foxhuls 1y ago
    Are you legitimately trying to compare alcohol to heroin?
    • DangitBobby 1y ago
      I think they are legitimately mocking the notion that we wouldn't all be better off without alcohol.
    • gloosx 1y ago
      I don’t want to spoil anything for you, but ethanol is actually a very reactive molecule — and in some ways, it acts similarly to opioids like heroin. It, among other things, stimulates endogenous opioid pathways, leading to the release of β-endorphins and activation of mu-opioid receptors. So, alcohol works indirectly, heroin directly – but both enhance opioid signalling. If you’re curious, this study explains it really well: https://pmc.ncbi.nlm.nih.gov/articles/PMC3728478/ https://pmc.ncbi.nlm.nih.gov/articles/PMC3728478/
      • rafaelero 1y ago
        Food can also indirectly enhance opioid signaling. What's your point?
        • gloosx 1y ago
          Food activates it within normal biological limits, alcohol and heroin artificially push the same system far beyond normal range, forcing the brain to compensate by downregulating receptors or reducing endogenous opioid production, so it's totally legit to compare alcohol to heroin
• tbossanova 1y ago
  Oh it definitely would
  • keanb 1y ago
    Hard disagree.