8 ms·

Polylaminin promotes regeneration after spinal cord injury (2010)

57 points by zac23or 1y ago

westurner 1y ago
"3D-Printed Scaffolds Promote Enhanced Spinal Organoid Formation for Use in Spinal Cord Injury" (2025) https://advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202404817 https://advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.20... .. https://news.ycombinator.com/item?id=45141972 https://news.ycombinator.com/item?id=45141972
westurner 1y ago
/? polyaminin https://www.google.com/search?client=ms-android-google&q=polyaminin https://www.google.com/search?client=ms-android-google&q=pol...
p33p 1y ago
This paper is from 2010. Can the OP discuss why this is relevant today.
- zac23or 1y ago
  Because of today's news https://www1-folha-uol-com-br.translate.goog/equilibrioesaude/2025/09/medicamento-brasileiro-inedito-tido-como-capaz-de-reverter-lesao-medular-e-apresentado-em-sp.shtml?_x_tr_sl=pt&_x_tr_tl=en&_x_tr_hl=pt-BR&_x_tr_pto=wapp https://www1-folha-uol-com-br.translate.goog/equilibrioesaud...
  - flyinglizard 1y ago
    I don't know what's wilder, regaining full functionality in spinal cord injuries or that URL.
Terr_ 1y ago
Tangentially: There's interesting research out there indicating that cellular repair is guided and promoted by the local electrical fields from surrounding tissues. For example: "Treating Scars After Burns With Pulsed Electric Fields in the Rat Model" - https://academic.oup.com/jbcr/article-abstract/45/6/1553/7728865 https://academic.oup.com/jbcr/article-abstract/45/6/1553/772... I wonder if we (or at least, our descendants) will figure out limb regrowth before we figure out functional immortality.
- wewewedxfgdf 1y ago
  So much stuff seems to work in rats and mice but not people. Perhaps we should genetically move humanity over time to be more rat like.
- CGMthrowaway 1y ago
  Wifi impact on plant growth https://www.youtube.com/watch?v=uCAKeIdyuVo https://www.youtube.com/watch?v=uCAKeIdyuVo
- brennanpeterson 1y ago
  Not sure on limbs, but for fast bone and tooth repair it works. https://www.nature.com/articles/srep31724 https://www.nature.com/articles/srep31724
- deleted 1y ago
  [deleted]

57 points by zac23or 1y ago

"3D-Printed Scaffolds Promote Enhanced Spinal Organoid Formation for Use in Spinal Cord Injury" (2025) https://advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202404817 https://advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.20... .. https://news.ycombinator.com/item?id=45141972 https://news.ycombinator.com/item?id=45141972

westurner 1y ago

/? polyaminin https://www.google.com/search?client=ms-android-google&q=polyaminin https://www.google.com/search?client=ms-android-google&q=pol...

p33p 1y ago

This paper is from 2010. Can the OP discuss why this is relevant today.

zac23or 1y ago
Because of today's news https://www1-folha-uol-com-br.translate.goog/equilibrioesaude/2025/09/medicamento-brasileiro-inedito-tido-como-capaz-de-reverter-lesao-medular-e-apresentado-em-sp.shtml?_x_tr_sl=pt&_x_tr_tl=en&_x_tr_hl=pt-BR&_x_tr_pto=wapp https://www1-folha-uol-com-br.translate.goog/equilibrioesaud...
- flyinglizard 1y ago
  I don't know what's wilder, regaining full functionality in spinal cord injuries or that URL.

Terr_ 1y ago

Tangentially: There's interesting research out there indicating that cellular repair is guided and promoted by the local electrical fields from surrounding tissues. For example: "Treating Scars After Burns With Pulsed Electric Fields in the Rat Model" - https://academic.oup.com/jbcr/article-abstract/45/6/1553/7728865 https://academic.oup.com/jbcr/article-abstract/45/6/1553/772... I wonder if we (or at least, our descendants) will figure out limb regrowth before we figure out functional immortality.

wewewedxfgdf 1y ago
So much stuff seems to work in rats and mice but not people. Perhaps we should genetically move humanity over time to be more rat like.
CGMthrowaway 1y ago
Wifi impact on plant growth https://www.youtube.com/watch?v=uCAKeIdyuVo https://www.youtube.com/watch?v=uCAKeIdyuVo
brennanpeterson 1y ago
Not sure on limbs, but for fast bone and tooth repair it works. https://www.nature.com/articles/srep31724 https://www.nature.com/articles/srep31724
deleted 1y ago
[deleted]