7 ms·
I thought lipid nanoparticles were less prone to generate a immune reaction.
by sampl3username 1y ago
I thought lipid nanoparticles were less prone to generate a immune reaction.
- justsee 1y agoLipid nanoparticle toxicity has long been an industry concern. In a profile of Moderna back in 2016, Katalin Karikó (instrumental in the development of mRNA vaccines) mentioned this issue: “I would say that mRNA is better suited for diseases where treatment for short duration is sufficiently curative, so the toxicities caused by delivery materials are less likely to occur” [1] [1] https://www.statnews.com/2016/09/13/moderna-therapeutics-biotech-mrna/ https://www.statnews.com/2016/09/13/moderna-therapeutics-bio...