7 ms·
The folks at Arc are trying to build this! https://arcinstitute.org/news/virtual-cell-model-state https://arcinstitute.org/news/virtual-cell-model-state
by andrewchoi 1y ago
The folks at Arc are trying to build this! https://arcinstitute.org/news/virtual-cell-model-state https://arcinstitute.org/news/virtual-cell-model-state
- dekhn 1y agoSTATE is not a simulation. It's a trained graphical model that does property prediction as a result of a perturbation. There is no physical model of a cell. Personally, I think arc's approach is more likely to produce usable scientific results in a reasonable amount of time. You would have to make a very coarse model of the cell to get any reasonable amount of sampling and you would probably spend huge amounts of time computing things which are not relevant to the properties you care amount. An embedding and graphical model seems well-suited to problems like this, as long as the underlying data is representative and comprehensive.