4 ms·

are you asking about methods to improve privacy of aggregated datasets? They seem to be not super popular with people in the field, I think because they sharply

are you asking about methods to improve privacy of aggregated datasets? They seem to be not super popular with people in the field, I think because they sharply curtail how data can be used compared to having access to datasets with no strong privacy guarantees. I think the maybe more impactful recent shift is toward "trusted research environments" where you get to work with a particular dataset only in a controlled setting with actively monitored egress.

robwwilliams 1y ago
Yes, that is the new UKBiobank approach. Homomorphic encryption enables standard GWAS workflows (not just summary stats) while “sharing” all genotypes and phenotypes. Richard Mott and colleagues have a paper and colleagues on this method; https://pubmed.ncbi.nlm.nih.gov/32327562/ https://pubmed.ncbi.nlm.nih.gov/32327562/