As long as you keep using frameworks, yes! Instead just use a base library to give you a cross-browser wrapper and few more utils, then develop the whole appli

As long as you keep using frameworks, yes! Instead just use a base library to give you a cross-browser wrapper and few more utils, then develop the whole application core layer on top it to separate it from your sandbox. Write all processing in core JavaScript unless you are trying to access DOM where the library (usually jQuery) wrappers would come into picture. This would give you immense power to control what you develop; will be highly scalable and of course, not to forget, performance. Don't even complain if you have server side frameworks which will generate JavaScript for you; that will never work and is only good till your project is in Mock-up (prototype) stage. The problem seems, you don't have good UI guys.