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From the first paper: "Conclusions Two vaccine doses provided high protection against SARS-CoV-2 infection and COVID-19 hospitalization with the Alpha and Delt
by guyzero 2y ago
From the first paper:
"Conclusions
Two vaccine doses provided high protection against SARS-CoV-2 infection and COVID-19 hospitalization with the Alpha and Delta variants with protection, notably against infection, waning over time. Two vaccine doses provided only limited and short-lived protection against SARS-CoV-2 infection with Omicron. However, the protection against COVID-19 hospitalization following Omicron SARS-CoV-2 infection was higher. The third vaccine dose substantially increased the level and duration of protection against infection with the Omicron variant and provided a high level of sustained protection against COVID-19 hospitalization among the +60-year-olds."
No indication of negative efficacy.
- ifyoubuildit 2y agoLook at the table on page 9 for 2 doses past 180 days. Negative efficacy is within the error bars. By no means a slam dunk, but it's there. EDIT: Also consider that the endpoint is "symptomatic infection", so it misses asymptomatic infections. The 3rd dose followup periods aren't long enough in this study to see what happens there.