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> However, in about 10% of the instances in which AlphaFold2 was “very confident” about its prediction (a score of at least 90 out of 100 on the confidence scal
by savingsPossible 2y ago
> However, in about 10% of the instances in which AlphaFold2 was “very confident” about its prediction (a score of at least 90 out of 100 on the confidence scale)
I wonder what that confidence score means... If it is 90% probability, then we'd expect it to be wrong 10% of the time
- COGlory 2y agoIf you're actually interesting, you can read about the scoring here: https://www.ebi.ac.uk/training/online/courses/alphafold/inputs-and-outputs/evaluating-alphafolds-predicted-structures-using-confidence-scores/plddt-understanding-local-confidence/ https://www.ebi.ac.uk/training/online/courses/alphafold/inpu... Long short, it's a lot more complex than just % probability the atoms have proper Cartesian coordinates.