5 ms·
every holy grail is 5 years away. i've been reading this for 20 years now.
by lawrence1 2y ago
every holy grail is 5 years away. i've been reading this for 20 years now.
- deleted 2y ago[deleted]
- spondylosaurus 2y agoHonestly IBD is one area where we've made massive progress in the past few decades. We went from having zero biologics (which means your only options were mediocre oral meds, long-term steroid use, or various -ectomies) to having dozens of biologics that each target one of a handful of major inflammatory pathways. Remicade was the first holy grail :)
- kbf 2y agoI started on Remicade, but sadly I was one of the few who didn’t see results and I managed to get a lot sicker while waiting for it to do its thing. I got put on Upadacitinib and so far I feel a lot better, if it keeps working this well then I’m very happy to just have a pill to take daily. It’s pretty new, but from what I’m hearing it’s very effective.
- spondylosaurus 2y agoFingers crossed for the new pill! I've also heard that JAK inhibitors work wonder for a lot of people who didn't get results from TNF inhibitors. And it's probably way easier to tinker with the dose if need be :P
- jpm_sd 2y agoUpadacitinib has been a huge success for someone in my family. Spectacularly effective. This is after trying the Specific Carbohydrate Diet, 5-ASAs, adalimumab, ustekinumab, and vedolizumab, none of which offered more than minor relief.
- jjtheblunt 2y agoi often thing such claims are progress updates from research groups dependent on government grants for funding, so they need to assert they will still need a next round of funding.