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I expected to read that and find it was a fluke accident. Instead, it reads like the scientists shrugged before the injection and said, “What’s the worst that c
by CSSer 2y ago
I expected to read that and find it was a fluke accident. Instead, it reads like the scientists shrugged before the injection and said, “What’s the worst that could happen?”
That’s unreal. It killed monkeys under similar circumstances and the kid wasn’t at his healthiest at the time of treatment either. Did they not care or was there some reason to believe that outcome was virtually improbable?
- dekhn 2y agoI honestly don't know what they were thinking. BTW, most gene vectors today are based on lentiviruses... specifically, from HIV. It took a few tries before they found a method to reliably remove all the bad bits from the vector. See https://www.nature.com/articles/s41375-018-0106-0 https://www.nature.com/articles/s41375-018-0106-0 and other articles on the evolution of HIV as a gene therapy vector.
- naasking 2y agoBioethics is a lot stricter than you think. They did not simply shrug and say that.