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The effect here seems to have little to do with gut microbiota: acetic acid itself induces the liver to stop making fats (lipogenesis) and start liberating fats
by vfvthunter 3y ago
The effect here seems to have little to do with gut microbiota: acetic acid itself induces the liver to stop making fats (lipogenesis) and start liberating fats into the blood (lipolysis). AcOH also by itself seems to decrease insulin resistance/increase insulin sensitivity, as well as downregulate gluconeogenesis. Several of the other studies in the bibliography confirmed this, and a couple even did tissue biopsies pre during and post to assess for changes in genetic expression of things like AMPK.