> we don't have any maps of neuron connectivity We do for a at least one classic, small-scale example: C. Elegans. Despite mapping the roughly 300 neurons, the

> we don't have any maps of neuron connectivity We do for a at least one classic, small-scale example: C. Elegans. Despite mapping the roughly 300 neurons, the simulation attempts I'm aware of weren't very fruitful. > with nearly the resolution required to do so. I agree this may be part of why. Accurate simulation may require replicating subtle behavior outside the neuron body. Further maps or simulation attempts may have since been made, and possibly with better results. Given I don't remember headlines about this, it's likely that any improvements weren't groundbreaking. I don't know enough about the roles of glia and inter-neuron (not interneuron) behavior to discuss this further beyond wild speculation. Nor does anyone, as far as I know. Gaining that knowledge would probably be necessary to build connectomes with sufficient accuracy for simulation.