5 ms·
As someone with severe Asian flush, with an overactive ADH gene (gene that converts of alcohol to acetaldehyde) and 2 defective ALDH2 alleles (gene that breaks
by jimmydef 3y ago
As someone with severe Asian flush, with an overactive ADH gene (gene that converts of alcohol to acetaldehyde) and 2 defective ALDH2 alleles (gene that breaks down acetaldehyde into harmless byproducts), I wish there is a way to repair these genes using MRNA. I don't feel even the mildest buzz from alcohol but I instantly get a hangover when I drink.
- Scoundreller 3y agomRNA injections won't do it. You'd need a CRISPR for that. And someway to get the rest of your body to take up the cells with the new genes, and you're a little late for most of your cells. I think you're better off searching for non-alcoholic alternatives in the short-medium term.