There is an episode in Andrew Hubermans' podcast which goes into the details of this. Overall if you are keeping your digestive track in "digestion mode" freque

There is an episode in Andrew Hubermans' podcast which goes into the details of this. Overall if you are keeping your digestive track in "digestion mode" frequently thus not letting it rest will eventually building up constant acid (to digest the food) resulting in reflux. The digestive track goes into "rest mode" about 3-4 hours after your most recent food intake.