9 ms·
The fact that AlphaFold is not able to predict effects of single mutations is well known in protein research community. For SOTA in this space, see Deepsequence
by yza 3y ago
The fact that AlphaFold is not able to predict effects of single mutations is well known in protein research community. For SOTA in this space, see Deepsequence (https://doi.org/10.1101/235655 https://doi.org/10.1101/235655) and ESM (https://doi.org/10.1101/622803 https://doi.org/10.1101/622803)