5 ms·

... in vitro and in 40 male mice.

• deleted 4y ago
  [deleted]
• fwlr 4y ago
  The effects of lions mane mushroom has been studied in humans before (https://examine.com/supplements/lionsmane/#research-breakdown https://examine.com/supplements/lionsmane/#research-breakdow...). This is a study specifically of the mechanism by which those effects arise.
  • cpncrunch 4y ago
    The one human trial there shows no difference between active and placebo groups. https://www.jstage.jst.go.jp/article/biomedres/31/4/31_4_231/_pdf/-char/en https://www.jstage.jst.go.jp/article/biomedres/31/4/31_4_231...
    • fwlr 4y ago
      Fantastic! With mice in vitro you had no idea if there was an effect, with this study you have evidence there is no effect!
    • dymk 4y ago
      > Our results show that HE intake has the possibility to reduce depression and anxiety and these results suggest a different mechanism from NGF-enhancing action of H. erinaceus. No, it says that there is a possible difference, but the mechanism is not what they thought it might be
      • cpncrunch 4y ago
        The abstract is just hype. Read the full text. There was no difference between groups. The study failed!