6 ms·
Wouldn't you only need two bits to encode C, G, A, and T?
by robert-boehnke 4y ago
Wouldn't you only need two bits to encode C, G, A, and T?
- dekhn 4y agoYes, two bits (assuming you only need to encode those four bases; unfortunately, biological reality requires FASTQ to encode other nucleotide values). There's even a format from UCSC called "2bit" (https://genome.ucsc.edu/goldenPath/help/twoBit.html https://genome.ucsc.edu/goldenPath/help/twoBit.html)