Meth is significantly different than regular amphetamine. Consider that simple changes in isomers can elicit radically different effects. A great example is lev

Meth is significantly different than regular amphetamine. Consider that simple changes in isomers can elicit radically different effects. A great example is levmetamfetamine (or l-meth), which is sold over the counter as a decongestant (as opposed to d-meth, the “fun” kind). Now, if the difference between a “left-handed” and “right-handed” meth molecule can be so great, it shouldn’t come as a surprise that adding a methyl group to regular amphetamine will change its effects considerably. This can be seen in the different receptor binding profiles (which receptors, where in the brain, and how strong or long the modulation is). Meth’s increased addictive and neurotoxic effects are owed to this difference in receptor binding.