Your comment reminded me of the podcast The Habitat (https://gimletmedia.com/shows/the-habitat https://gimletmedia.com/shows/the-habitat) about a (real-life) Ma

Your comment reminded me of the podcast The Habitat (https://gimletmedia.com/shows/the-habitat https://gimletmedia.com/shows/the-habitat) about a (real-life) Mars mission simulation. Your last point, about the possibility of rescue, is really interesting and I wonder if there's any clever ethical way to control for that in a study like the one in the podcast.