This is hardly the first time that Glucosamine use is associated with lower cancer/mortality risks: https://ard.bmj.com/content/79/6/829 https://ard.bmj.com/co

This is hardly the first time that Glucosamine use is associated with lower cancer/mortality risks: https://ard.bmj.com/content/79/6/829 https://ard.bmj.com/content/79/6/829 - Associations of regular glucosamine use with all-cause and cause-specific mortality: a large prospective cohort study https://pubmed.ncbi.nlm.nih.gov/33219063/ https://pubmed.ncbi.nlm.nih.gov/33219063/ - Glucosamine/Chondroitin and Mortality in a US NHANES Cohort https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175750/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175750/ - Use of Glucosamine and Chondroitin and Lung Cancer Risk in the VITamins And Lifestyle (VITAL) Cohort https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870876/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870876/ - Glucosamine Use and Risk of Colorectal Cancer: Results from the Cancer Prevention Study II Nutrition Cohort https://cancerci.biomedcentral.com/articles/10.1186/1475-2867-9-25 https://cancerci.biomedcentral.com/articles/10.1186/1475-286... - Glucosamine suppresses proliferation of human prostate carcinoma DU145 cells through inhibition of STAT3 signaling (in vitro) https://www.pharmacytoday.org/article/S1042-0991(17)30735-1/fulltext https://www.pharmacytoday.org/article/S1042-0991(17)30735-1/... - Glucosamine and chondroitin decrease colorectal cancer risk Some of those still showed significant correlation even when accounting for NSAID use however there have been other studies where the correlation significance disappears when accounting for NSAIDs: https://www.nature.com/articles/s41598-018-20349-6 https://www.nature.com/articles/s41598-018-20349-6 Mortality reduction with glucosamine has been directly shown in more controlled studies on other organisms such as nematodes and mice, but may do so through a path that hasn't been shown to work in humans: https://www.nature.com/articles/ncomms4563 https://www.nature.com/articles/ncomms4563 And in an actual double blind study glucosamine (+ chondroitin) use was found to lower serum levels of C-reactive protein in men and women: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0117534 https://journals.plos.org/plosone/article?id=10.1371/journal... (small sample size)