5 ms·
Interesting you're so focused on the "vaccine hesistancy" side of the fence. Do you have any concerns about people using their prestigious degrees and credentia
by __blockcipher__ 5y ago
Interesting you're so focused on the "vaccine hesistancy" side of the fence. Do you have any concerns about people using their prestigious degrees and credentials to frighten the population completely out of proportion with their actual risk from a pathogen, in order to persuade them to comply with top-down public health measures?
It sounds a lot like you just don't like the conclusion that this classic paper leads to: that the "societal benefit" of mass vaccination with an imperfect vaccine is not nearly as clear-cut as many have been led to believe.
My advice to people is to treat the vaccines as a personal risk reduction tool and little else. The only way to actually guarantee you won't infect someone you interact with, is to have acquired (and recovered from) the natural SARS-2 virus, which will build robust immunity. As far as immunity to reinfection, looking at antibodies alone, IgG levels stay seropositive for ~3.5 years:
https://www.medrxiv.org/content/10.1101/2020.07.18.20156810v1.full.pdf https://www.medrxiv.org/content/10.1101/2020.07.18.20156810v...
> Based on these half-life data, we estimate that the median times for IgM, IgA and IgG to become seronegative are 4.59 (IQR 4.12-5.03), 7.78 (IQR 6.71-9.16) and 42.72 (IQR 33.75-47.96) months post disease onset.
> This study suggests that SARS-CoV-2 infection induces robust neutralizing and binding antibody responses in patients and that humoral immunity against SARS-CoV-2 acquired by infection may persist for a relatively long time.
and furthermore once those IgG levels fade you will still have immunological memory, which lasts basically forever and allows your system to much more rapidly and effectively respond to future infection, leading you to have a much lower peak viral load, lessened symptoms (usually fully asymptomatic) and therefore a near inability to transmit the virus.
For example for the 1918 flu, immunological memory has been shown to persist 60+ years later: https://www.cidrap.umn.edu/news-perspective/2008/08/researchers-find-long-lived-immunity-1918-pandemic-virus https://www.cidrap.umn.edu/news-perspective/2008/08/research...
- f6v 5y agoThere’s no way for public to make vaccination decisions on their own. They just don’t have the knowledge and the skills to interpret the data. I mean, it’d be silly if we said: “Hey, you’ve got colon cancer? You could do chemo or surgery. Your pick!”. And unlike cancer, pandemic has impact not only on your health, but on others too.
- slumpt_ 5y agoThis is a really sad reality. The internet has empowered us as a civilization but also emboldened a lot of folks who haven’t the expertise to digest immunology research. Joe Rogan and an afternoon on Google Scholar isn’t a replacement for a couple decades of immunology work.