7 ms·

one thing about the Oxford vaccine is that when vaccinated you are still able to pass on the virus , despite having the anti-bodies to fight it. It's excellent

one thing about the Oxford vaccine is that when vaccinated you are still able to pass on the virus , despite having the anti-bodies to fight it. It's excellent news nonetheless edited with some references https://www.telegraph.co.uk/global-health/science-and-disease/doubts-oxford-vaccine-fails-stop-coronavirus-animal-trials/ https://www.telegraph.co.uk/global-health/science-and-diseas... https://www.independent.co.uk/news/health/coronavirus-vaccine-oxford-trials-concerns-transmission-astrazeneca-latest-a9521241.html https://www.independent.co.uk/news/health/coronavirus-vaccin...

djsumdog 6y ago
Why is that the case with the Oxford vaccine? Can you elaborate?
- deleted 6y ago
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- t2riRXawYxLGGYb 6y ago
  I'm curious what they meant as well. Perhaps what they meant was the potential period where the virus is replicating in the body before the immune system detects it and kills it. I suppose even someone with the vaccine would have a very short-lived period of viral replication? Or perhaps they simply meant that humans could be fomites (eg, it gets on someone's hand, then they shake your hand, etc?) Honestly I'm just guessing here. I suspect this is not a real concern.
CyanLite2 6y ago
This is a little bit of a misnomer. Anybody can pass on the virus. If you have it in your nose and you sneeze, you'll spread it everywhere. If you have it on your hands and you touch high-traffic surface areas, you'll spread it. The point is that if a high number of people are vaccinated, then it won't matter if the virus fragments are spread, as long as it's not causing disease then it doesn't matter.
zwily 6y ago
That was true for the monkeys that were challenged with huge viral loads. We don’t know if it will still be true for humans who encounter normal loads.
ageitgey 6y ago
You are reporting very misleading information as if it were a fact. No one knows that to be true in humans, not even the creators of the vaccine. In a very limited test of a small number of monkeys who were directly injected with high levels of the virus, those monkeys still had the virus in their noses and might have been able to pass it on (in theory). That has very little value in telling us what the vaccine will do in humans in the real world. No one will know until the Phase 3 trials are complete. It's still possible that the vaccine will be totally effective, partially effective or completely ineffective in protecting humans. That's why we need the Phase 3 trial results to know if this vaccine "works".

djsumdog 6y ago

Why is that the case with the Oxford vaccine? Can you elaborate?

deleted 6y ago
[deleted]
t2riRXawYxLGGYb 6y ago
I'm curious what they meant as well. Perhaps what they meant was the potential period where the virus is replicating in the body before the immune system detects it and kills it. I suppose even someone with the vaccine would have a very short-lived period of viral replication? Or perhaps they simply meant that humans could be fomites (eg, it gets on someone's hand, then they shake your hand, etc?) Honestly I'm just guessing here. I suspect this is not a real concern.

CyanLite2 6y ago

This is a little bit of a misnomer. Anybody can pass on the virus. If you have it in your nose and you sneeze, you'll spread it everywhere. If you have it on your hands and you touch high-traffic surface areas, you'll spread it. The point is that if a high number of people are vaccinated, then it won't matter if the virus fragments are spread, as long as it's not causing disease then it doesn't matter.

zwily 6y ago

That was true for the monkeys that were challenged with huge viral loads. We don’t know if it will still be true for humans who encounter normal loads.

ageitgey 6y ago

You are reporting very misleading information as if it were a fact. No one knows that to be true in humans, not even the creators of the vaccine. In a very limited test of a small number of monkeys who were directly injected with high levels of the virus, those monkeys still had the virus in their noses and might have been able to pass it on (in theory). That has very little value in telling us what the vaccine will do in humans in the real world. No one will know until the Phase 3 trials are complete. It's still possible that the vaccine will be totally effective, partially effective or completely ineffective in protecting humans. That's why we need the Phase 3 trial results to know if this vaccine "works".