5 ms·
It should help alleviating the symptoms, but is in no way a antiviral. There's a phase 3 trial for treating pneumonia associated with coronavirus. This is base
by Amygaz 7y ago
It should help alleviating the symptoms, but is in no way a antiviral.
There's a phase 3 trial for treating pneumonia associated with coronavirus. This is based on prior work showing anti-inflammatory response in rheumatoid arthritis (https://www.ncbi.nlm.nih.gov/pubmed/8278823 https://www.ncbi.nlm.nih.gov/pubmed/8278823).
Note that the trial is happening in China (https://clinicaltrials.gov/ct2/show/NCT04261517 https://clinicaltrials.gov/ct2/show/NCT04261517), where the barriers of entry and approval are quite low.
- mirimir 7y ago> After randomization, subjects take hydroxychloroquine 400mg per day for 5 days, also take conventional treatments. Huh. I'm on 200mg/day for rheumatoid arthritis. I wonder if I ought to double dose for a while.
- Amygaz 7y agoSorry for the late reply: I don't see how it would prevent infection. It could be useful post-infection, to prevent complications and inflammation. Compared that with the standard of care right now which is simply observing the patient during their recovering. There are a fair amount of studies who took the initial in vitro results (i.e. cell culture) suggesting non-specific antiviral activity (at that level coca-cola is also an antiviral, antimicrobial, and antitumoral, by the way), into animal or human, and they just did not pan out, because it isn't an antiviral.
- mirimir 7y agoThank you. I'll ask my rheumatologist about increasing the dose. In case I get infected, have trouble breathing, and can't get hospital care.