8 ms·
So there are products on the market already or no one has a product on the market yet?
by Circuits 7y ago
So there are products on the market already or no one has a product on the market yet?
- arkades 7y agoPhase 1 study. Years from market.
- ConcernedCoder 7y ago...or we could just start eating Pomegranates?
- pgtan 7y agowho doesn't?
- DoofusOfDeath 7y agoWe can "just" start eating Pomegranates, absolutely. Personally, I find them pretty tasty, and they remind me of the Greek myth of Persephone's abduction by Hades. So I'm all for them. But how much you'd need to eat for a clinically noteworthy benefit is the question. That's what the follow-on studies are for.
- arkades 7y agoIf they’ve raised capital for a series of clinical trials, you can reasonably assume the doses at which they expect to see clinical effects are much higher than you’re likely to get just from food ingestion - otherwise their competition would just be pomegranate juice pills or something, sold as a food supplement and requiring no trials of safety or efficacy. They’d never have been able to raise a cent. In other words, no one would fund a penicillin trial if they thought people could get by eating moldy bread from GNC.
- derefr 7y agoI don’t know. The dose of broccoli you need to see clinical effects from the sulforaphane it contains is extremely high, but concentrated sulforaphane capsules are sold as a food supplement without needing to go through any FDA process. What criterion does the FDA use to distinguish a food-derived chemical that needs to be treated as a drug, from one that’s still just seen as an extract/essence of the food itself, and therefore can be treated as a supplement? It seems very opaque to me.
- DSingularity 7y agoThe article states that Urolithin-A is not produced by everybody. That acid in these fruits needs to be converted to UA in our gut. So no, it’s not always as simple as eating these fruits.
- strainer 7y agoHowever at the same time, the gut is so confoundingly complicated that substances in concentrated tablet form are often less readily absorbed than less concentrated amounts occurring in food.
- egypturnash 7y agoFirst we should see if this study was funded by that one giant pomegranate farm in California. If Wikipedia is correct, we should start eating yellow raspberries instead; they offer about seven times as much of the compound this study is investigating the effects of. https://en.wikipedia.org/wiki/Urolithin_A#Dietary_sources https://en.wikipedia.org/wiki/Urolithin_A#Dietary_sources
- deleted 7y ago[deleted]
- gpm 7y agoQuite possibly pomegranate... It's unclear how much it has though.
- akimball 7y agoThere are raspberries and pomegranates on the market, yes.