Why do you think it's basically zero? To me, it just seems like an (admittedly difficult) engineering problem that we're likely to make a lot of progress on. I

Why do you think it's basically zero? To me, it just seems like an (admittedly difficult) engineering problem that we're likely to make a lot of progress on. I'm currently studying biology and it's pretty amazing what humans have discovered in the last ~100 years about how the body works at the atomic level. As a meta-point, I find it fascinating how nearly completely divergent our bayesian priors are (I think our chances of counteracting all of those forces you mentioned are, on a long enough timeline and assuming we're not destroyed and we have sufficient energy, greater than 90%).