For SPAs, I mostly use ClojureScript with reagent and re-frame nowadays. Reagent is a ClojureScript wrapper for react, and re-frame is a library for state mana

For SPAs, I mostly use ClojureScript with reagent and re-frame nowadays. Reagent is a ClojureScript wrapper for react, and re-frame is a library for state management, where you dispatch events kind of like in redux. It's most productive and intuitive environment I've come across. Very little boilerplate. I haven't tried serverside rendering with it though. There's also re-natal if you want to use react-native, but I haven't tried this either, so I can't vouch for it.