I'm completely unfamiliar with this stuff, but from the article: "In risk individuals, a thymine (T) is replaced by a cytosine (C) nucleobase, which disrupts r

I'm completely unfamiliar with this stuff, but from the article: "In risk individuals, a thymine (T) is replaced by a cytosine (C) nucleobase, which disrupts repression of the control region and turns on IRX3 and IRX5. This then turns off thermogenesis, leading to lipid accumulation and ultimately obesity... Switching the C to a T in risk individuals turned off IRX3 and IRX5, restored thermogenesis to non-risk levels, and switched off lipid storage genes." So yes, CC is taken to mean "risk" and CT is likewise "non-risk". As always, one finding doesn't indicate ultimate truth, so take this all with a grain of salt (or not, depending on what 23andMe has to say about your sodium intake).